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About Our Donors
Anonymous Donor Program

Our donors are university students, college graduates, or post graduate students. Our qualification process is vigorous and includes everything from an extensive medical evaluation, genetic testing, and psychological evaluation. Strict criteria are set for the acceptance of prospective donors. Nine out of ten potential donors are denied participation in our program. All of our donors receive a medical genetic evaluation including a physical examination, a detailed family history and ancillary tests.

Donor eligibility requirements

All of our semen donors meet relevant FDA eligibility requirements. All tests are performed in CLIA certified laboratories using FDA approved tests. The donors must test negative or non-reactive to the required tests on initial evaluation. The donor specimens are held in quarantine for at least 6 months after which the donor is retested and found to be negative or non-reactive prior to the release of the samples for clinical use. A summary of records used to determine donor eligibility will accompany each specimen shipment. This record lists each of the tests and results.

Medical History & Physical Examination:

An in-person, detailed personal and three generation family medical and social history review is conducted with prospective donors by medical staff members to identify any known risk factors for infectious diseases or genetic conditions. Those with no known genetic or infectious disease risks then undergo a thorough examination to look for any physical evidence of such diseases. Upon review of the history of the medical director and geneticist determine if any additional testing is necessary.


The laboratory tests performed during the initial screening include the following:

  • ABO grouping & Rh type (blood type).

  • Chemistry panel with liver enzymes.

  • Lipid Panel.

  • Complete blood count.

  • Urinalysis and urine culture.

  • A complete semen analysis which includes evaluation for volume, sperm concentration, sperm motility and morphology, a post-thaw semen analysis to assess the survival rate of sperm after the freezing process.

Infectious Diseases:

  • HIV 1/0/2 Ab.

  • HTLV-I/II Ab.

  • Hepatitis B virus (including hepatitis B surface antigen and antibody to hepatitis B core antigen).

  • Hepatitis C virus.

  • Nucleic acid testing for HIV 1, Hepatitis B and C viruses.

  • Syphilis.

  • Cytomegalovirus (CMV).

  • Chlamydia.

  • Gonorrhea.

Genetic Testing:

All Donors:
  • Chromosome Analysis.

  • Cystic Fibrosis (testing for 99 mutations).

  • Hemoglobin electrophoresis for hemoglobinopathies such as Thalassemia, Sickle Cell Disease and other blood abnormalities.

  • Spinal Muscular Atrophy (SMA).

Donors of Jewish Ancestry:
  • Bloom Syndrome.

  • Canavan Disease.

  • Familial Dysautonmia.

  • Fanconi Anemia type C.

  • Gaucher Disease.

  • Mucolipidosis IV.

  • Niemann-Pick Disease.

  • Tay-Sachs Disease.

Donors of French Canadian ancestry:
  • Tay-Sachs Disease.

Psychological Screening:
  • Our semen donors undergo psychological screening by a licensed clinical psychologist.

Continuity of Assessments:
  • Infectious disease testing is repeated every 3 months and the history and physical examinations are performed every 6 months while the donor participates in our program.

  • All frozen donor semen is quarantined for a period of 6 months, at which time the donor is retested and must be found negative for all infectious diseases prior to release of the samples.

Specimen Quality/Type:

Repro Lab is committed to providing donor semen specimens of the highest quality. We evaluate each specimen prior to release to ensure that it mets our high quality standards. A post thaw analysis of sperm count, motility, and grade value is included with every donor specimen shipment. IUI specimens are processed and ready for intrauterine insemination.

ICI / IUI Vials:

Both standard ICI specimens (specimens prepared for intracervical insemination) and IUI ready specimens (specimens prepared for intrauterine insemination) are available.

ICI specimens have a volume of 0.8 to 1.2cc per vial. The post thaw motility is a minimum of 30% and we guarantee a minimum of 20 million motile sperm/ml.

IUI ready specimens have a volume of 0.5 to 0.7cc per vial. The post thaw motility is a minimum of 30% and we guarantee a minimum of 24 million motile sperm/ml.

Identification Systems:

Our stringent specimen identification processes are a combination of electronic systems and repeated physical confirmation. Our reproductive cryotechnology specialists are experienced, efficient professionals who rigidly adhere to identification protocols.

Racial Coding System:

Racial coding systems help to identify the race of the donor. Color-coded cap inserts are on all our donors cryovials: White caps for Caucasian donors Brown caps for Black donors; Yellow caps for Asian donors; and Orange caps for Hispanic donors.


332 East 30th Street, New York NY 10016
Phone (212) 779-3988   Fax (212) 779-3907